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    Neuromuscular blockers, Pharmaceutical Biotechnology solution for terminate to ARDS arising from Covid-19

  • Mojtaba Goodarzi,1,* Ali Najafi,2
    1. Farhangian University
    2. Farhangian University


  • Introduction: With the ungovernable spread covid-19, humans after failure in controlling of proliferation process, sought to reduce the number of deaths caused by virus. Inflammation of lung tissue and make Acute respiratory distress syndrome (ARDS) and reduce SPO2 is the main cause of death of Coronavirus patients, if a person can tolerate ARDS while having coronavirus, probability of survival is greatly increased.
  • Methods: The method of this research is based on case reports files as well as books and articles on virology and clinical pharmacy.
  • Results: Neuromuscular blockers are based on acetylcholine receptors and are made using in vitro pharmaceutical biotechnology. The results of this study show that the use of Neuromuscular blockers in Coronavirus patients causes a feeling of relaxation, prevention of stress and anxiety caused by the progression of the disease. One of the problems of patients with Coronavirus disease is the significant activity of the immune system to fight the virus, increased secretion of lymphocytes in the body and thus increased inflammation in various tissues of the body, This increase inflammation in people with underlying hypertension or diabetes can increase the risk of ischemia in vital organs, such as heart and brain, Neuromuscular blockers reduce heart rate by acting on myocardial cells, thereby reducing the risk of stroke in patients with Coronavirus disease. The main use of Neuromuscular blockers in this context is to increase tolerance in a person with ARDS. Neuromuscular blockers reduce activity in the intercostal muscles and diaphragm, as a result, if a person with Coronavirus disease suffers from ARDS, it can breathe with less pain and more easily withstand the pressure of a mechanical ventilator, resulting in more days to live and Make recovery process be easier.
  • Conclusion: Early administration of Neuromuscular blockers means that the patient with Coronavirus will not need to go to artificial sleep for use the mechanical ventilator, will breathes with less pain and healing process is faster.
  • Keywords: Neuromuscular blockers, Coronavirus, ARDS, Pain