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    Comparison of the results of biological dressing treatment of xenoderm with traditional treatment method in large burns

  • Zeinab Sadat Moosavi Fard,1,*
    1. Department of Nursing, School of nursing University of Bandar Abbas, Islamic Azad University , Iran.


  • Introduction: Burns are an important cause of death and disability in the world and today biological dressing is an important part of burn treatment in advanced centers. With this method, the percentage of mortality in comparison with the level of burn from 50% mortality in 30% burn has reached the same amount in 80% burn. Due to the lack of experience in the widespread use of biological dressings in developing countries, the aim of this study was to compare the results of the use of biological dressings with traditional methods in patients with extensive burns.
  • Methods: In this study, 118 patients with burns between 75-75% of body surface area were studied. Patients were randomly divided into two groups. In the first group, patients were not satisfied with the preparation of xenoderm and were treated by traditional methods. In the second group, patients were satisfied with the preparation of xenoderm and the treatment of burns was performed by biological dressing.
  • Results: The mortality rate in the traditional method (53 patients) was 19 (35%) and in the biological dressing method (65 patients) was 7 (10.8%) (p = 0.001). If the deceased were excluded, the mean length of hospital stay was 31.3 days in the traditional group versus 18.2 days in the biological dressing group (p = 0.0005), the number of dressings in the traditional group was 22.1 vs. 9.9 in the biological dressing group (p = 0.005).
  • Conclusion: The results of this study show that biological dressing increases patient survival, reduces hospital stay and reduces daily extensive dressings. A randomized clinical trial study is recommended.
  • Keywords: Pig skin, Xenoderm, Extensive burn, Biological dressing, Early excision