the effect of crisper on the treatment of diseases
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zahra roozegar,1 ali hajifard,2 mostafa daneshi,3,*
1. islamic azad university zahedan
2. islamic azad university zahedan
- Introduction: Background; Today, efforts to achieve technology in various fields are increasing. One of the fields that has attracted a lot of attention is genetic engineering and gene therapy. The genome is the command post of living organisms, so in order to change the structure of organisms, it is necessary to make changes in their genes. Crisper is a tool for gene modification and the purpose of this article is to review the effect of crisper on the treatment of various diseases.
- Methods: Research Method؛ Relevant information was searched from Pub med, Scopus, Google Scholer databases; And data analysis was performed qualitatively.
- Results: findings; Crispers are used in many different ways today. One of the uses of Crisper is to use them in diseases including cancer. Crisper is an adaptive immune system in bacteria that enables them to detect virus DNA and then destroy it. It is part of the Crisper system called cas9, which has the ability to search, cut, and transform virus DNA in a specific way. This technology allows scientists to make changes in cell DNA. The cas9 protein is an enzyme for DNA cleavage that allows it to detect genomes in cells.
- Conclusion: Conclusion; Crispers can be used in various fields such as antibiotic production and in agriculture by changing traits such as flower color. Biologists began large-scale experiments not only because of Crisper's great abilities but also because Crisper is more cost-effective than other genome editing methods.
- Keywords: Keywords; DNA evolution, genome modification, Crisper, biotechnology, Cas9
